Study Findings on Stroke Detailed by Researchers at Mudanjiang Medical University (Analysis of the expression level and predictive value of CLEC16A|miR-654-5p|RARA regulatory axis in the peripheral blood of patients with ischemic stroke based...).

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Zdroj: Genomics & Genetics Weekly; 5/3/2024, p1708-1708, 1p
Abstrakt: Researchers at Mudanjiang Medical University in China have conducted a study on the expression level and predictive value of the CLEC16A|miR-654-5p|RARA regulatory axis in the peripheral blood of patients with ischemic stroke. The study utilized bioinformatics analysis and real-time fluorescence quantitative qRT-PCR experiments to identify differentially expressed circRNAs, miRNAs, and mRNAs associated with ischemic stroke. The researchers constructed a circRNA-mediated competitive endogenous RNA (ceRNA) regulatory network and validated the CLEC16A|miR-654-5p|RARA axis as a key component of this network. The study provides new insights into the pathogenesis of ischemic stroke. [Extracted from the article]
Databáze: Complementary Index