| Abstrakt: |
A recent study conducted at the University of Pretoria proposes a unifying hypothesis for the genetic dynamics underlying neuropsychiatric disorders (NPDs). The researchers suggest that the extensive clinical and molecular heterogeneity observed in NPDs may be due to downstream effects initiated by a smaller group of genomic higher-order alterations in response to stress. These alterations include chromosomal common fragile sites (CFS), microRNAs, gene copy number variants (CNVs), and other structural features. By studying these features, the researchers believe that a better understanding of the genetics of NPDs can be achieved. For more information, the full article can be accessed for free through the provided link. [Extracted from the article] |
