Research on Prostate Cancer Reported by a Researcher at University of Laval (An Extracellular Matrix Overlay Model for Bioluminescence Microscopy to Measure Single-Cell Heterogeneous Responses to Antiandrogens in Prostate Cancer Cells).

Předmět:	EXTRACELLULAR matrix BIOLUMINESCENCE PROSTATE cancer RESEARCH personnel ANTIANDROGENS
Zdroj:	Clinical Oncology Week; 4/23/2024, p1070-1070, 1p
Abstrakt:	A study conducted at the University of Laval in Quebec, Canada, has developed a new model for studying prostate cancer at the single-cell level. The researchers introduced an extracellular matrix-Matrigel (ECM-M) culture model that improved cellular tracking during bioluminescence single-cell imaging and enhanced cell viability. This model allowed for the monitoring of androgen receptor (AR) activity and the assessment of heterogeneous single-cell treatment responses to antiandrogens in prostate cancer cells. The study concluded that this approach provides valuable insights into the dynamic nature of prostate cancer treatment responses. [Extracted from the article]
Databáze:	Complementary Index
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