Translational Research and Health Equity: Gene Therapies for Sickle Cell Disease as a Case Study.

Autor:	Majumder, Mary A., Fasipe, Titilope
Předmět:	SICKLE cell anemia TRANSLATIONAL research GENE therapy HEALTH equity CELLULAR therapy
Zdroj:	Ethics & Human Research; May2024, Vol. 46 Issue 3, p34-39, 6p
Abstrakt:	In August of 2023, the National Academies of Science, Engineering, and Medicine published a timely report titled "Toward Equitable Innovation in Health and Medicine: A Framework." Here, we review some of the key contributions of the report, focusing on two dimensions of equity: input equity and deployment equity. We then use the example of new gene therapies to treat sickle cell disease (SCD) as a case study of input and deployment equity in translational research. The SCD case study illustrates the need for a kind of translational bioethics with deep understanding of lived experiences and clinical realities as well as a high degree of economic and policy sophistication. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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