| Autor: |
Hafez Ahmed, Mohamed Zaeim, Helmy Saad, Reham Helmy Amin, Gadalla, Ahmad, Ibrahim Thabet, Ramadan Hassan, Elshenawy Elsisi, Ahmed Abdrabo, Ahmed Mohamed, Ahmed Abdel Nasser, Abdallah, Mohamed Gaber, Shikhon, Tarek, Mohmmed Maged, Hussien Eleimy Hussien, Hassan Elfiky, Muhammad Abdelbaeth, Hassan, Marwa Fekry, Abdelraheem, Fatma Mahmoud, Hegazy, Ghada Adel |
| Předmět: |
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| Zdroj: |
Clinical & Experimental Hepatology; 2024, Vol. 10 Issue 1, p30-38, 9p |
| Abstrakt: |
Aim of the study: Jaundice in newborns is a sign of skin and sclera pigmentation. Hyperbilirubinemia and these phenomena do, however, have a relationship. According to many clinical studies, elevated blood bilirubin and low vitamin E (VE) levels in newborns are associated. The aim of the study was to investigate the association of oxidative stress of neonatal hyperbilirubinemia in patients who underwent phototherapy with additional vitamin E supplementation (25 mg/kg/day over the course of three days) and patients without additional vitamin E. Material and methods: A set of 100 neonatal indirect hyperbilirubinemia patients was enrolled at neonatal intensive care units (NICUs) of the pediatric departments at Al Azhar University Hospitals during the period from February 2021 to October 2022 after obtaining signed written informed consent of all neonates' parents with an explanation of the aim of study. Material and methods: A set of 100 neonatal indirect hyperbilirubinemia patients was enrolled at neonatal intensive care units (NICUs) of the pediatric departments at Al Azhar University Hospitals during the period from February 2021 to October 2022 after obtaining signed written informed consent of all neonates' parents with an explanation of the aim of study. Conclusions: Vitamin E supplementation has an important role in treatment of indirect hyperbilirubinemia in neonates. Early administration of vitamin E in preterm neonates resulted in a significant decrease of serum bilirubin and increased total antioxidant capacity. Vitamin E supplementation in full term decreased the duration of phototherapy. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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