Autor: |
van Liere, E., Ramsoekh, D., Daulton, E., Dakkak, M., Van Lingen, J., Dekker, E., Jacobs, M., Koornstra, J. J., Kuijvenhoven, J., Van Leerdam, M., Spaander, M., Covington, J., De Boer, N. |
Předmět: |
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Zdroj: |
Endoscopy; 2024 Supplement 2, Vol. 56, pS234-S234, 1p |
Abstrakt: |
This article discusses a prospective multicentre study that aimed to determine if non-invasive faecal volatile organic compounds (VOCs) could be used to detect colorectal neoplasia in individuals with Lynch syndrome. The study involved collecting faecal samples from individuals prior to surveillance colonoscopy and analyzing them using field asymmetric ion mobility spectrometry (FAIMS) and machine learning techniques. The results showed that faecal VOC patterns had a high sensitivity and moderate specificity for detecting relevant neoplasia in Lynch syndrome. The study suggests that faecal VOCs could potentially be used as a diagnostic test for personalized colonoscopy surveillance in Lynch syndrome. [Extracted from the article] |
Databáze: |
Complementary Index |
Externí odkaz: |
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