| Autor: |
Taha, Ali, Kadhim, Mustafa M., Naser, Sanarya Thamer, Majdi, Ali, Abdullaha, Sallal A.H, Hachim, Safa K., Abdulwahid Abdulhussain, Munthir, Mahdi Rheima, Ahmed |
| Předmět: |
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| Zdroj: |
Computer Methods in Biomechanics & Biomedical Engineering; May2024, Vol. 27 Issue 6, p765-774, 10p |
| Abstrakt: |
The Ni and Co doping effect on the ciclopirox (CPX) drug delivery performance of a ZnO nanosheet (ZnO-NS) was investigated theoretically. Doping Ni and Co metals into the ZnO-NS increased the adsorption energy of CPX from −7.9 to −27.4 and −31.7 kcal/mol, respectively. The CPX adsorption reduced the ZnO-NS gap (Eg) from 3.81 to 3.46 eV, while the CPX adsorption reduced the Eg of the Ni- and Co-doped ZnO-NS from 2.74 and 2.68 eV to 1.87 and 1.71 eV, respectively. The CPX adsorption performance increased after doping process. A drug release mechanism was introduced in cancerous tissues based on the PH. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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