| Abstrakt: |
This article explores the use of thioether-containing ligands in catalysis applications. Thioether ligands, which contain a sulfur atom, have traditionally been less considered due to their lower donor and acceptor character compared to phosphorus ligands. However, ligands with a low degree of oxidation and a combination of sulfur with another heteroatom have shown promise in generating interesting catalysts. The article provides examples of enantioselective and non-enantioselective reactions using thioether ligands and discusses the advantages of combining sulfur with another heteroatom. The paper is organized based on the type of heteroatom that accompanies the thioether function, such as phosphorus and nitrogen. Various catalytic systems involving thioether ligands for different organic transformations are discussed, including dihydroboration, cyclopropanation, silyl-hydrogen insertion, C-H functionalization, and C-H alkenylation. The ligands play a crucial role in enhancing the activity and selectivity of the catalysts, and they have been successfully applied to a wide range of substrates. Mechanistic studies have provided insights into the reaction pathways and the role of the ligands in facilitating the transformations. The article highlights the potential of thioether-functionalized ligands in metal-catalyzed reactions and suggests a promising future for sulfur in catalysis. [Extracted from the article] |
