| Abstrakt: |
A recent report from Virginia Commonwealth University explores the signaling pathways used by Treponema denticola, a bacterium associated with periodontitis, to adapt to its environment. The study focuses on the role of bis-(3'-5') cyclic diadenosine monophosphate (c-di-AMP), a nucleotide secondary messenger, in regulating T. denticola physiology. The researchers identified enzymes involved in c-di-AMP synthesis and hydrolysis, as well as a putative receptor protein. They also found that c-di-AMP negatively regulates potassium uptake in hypoosmotic solutions. This study provides valuable insights into the cellular processes of T. denticola and its adaptation mechanisms. [Extracted from the article] |
