Study Results from University of Memphis Update Understanding of Acinetobacter baumannii (Chitosan Membranes Stabilized with Varying Acyl Lengths Release Cis-2-Decenoic Acid and Bupivacaine at Controlled Rates and Inhibit Pathogenic Biofilm).

Předmět:	ACINETOBACTER baumannii BUPIVACAINE GRAM-negative aerobic bacteria CHITOSAN AEROBIC bacteria
Zdroj:	Drug Week; 4/16/2024, p2973-2973, 1p
Abstrakt:	A study conducted by researchers at the University of Memphis focused on the release of therapeutics from wound care biomaterials and their antimicrobial activity against pathogens such as Staphylococcus aureus, Acinetobacter baumannii, and Pseudomonas aeruginosa. The study found that electrospun chitosan membranes (ESCMs) loaded with anti-biofilm agent cis-2-decenoic acid (C2DA) and local anesthetic bupivacaine were effective in reducing biofilm formation. The combination of therapeutics released from the modified ESCMs showed promising results in preventing biofilm formation for selected strains. This research provides valuable insights into potential treatments for burn victims and the challenges posed by bacterial infections. [Extracted from the article]
Databáze:	Complementary Index
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