Reports from Federal University Pelotas Add New Data to Findings in Acinetobacter baumannii (The Synergic and Addictive Activity of Biogenic Silver Nanoparticle Associated With Meropenem Against Carbapenem-resistant Acinetobacter Baumannii).

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Zdroj: Drug Week; 4/16/2024, p1944-1944, 1p
Abstrakt: A recent study conducted at Federal University Pelotas in Brazil has found that the combination of biogenic silver nanoparticles (Bio-AgNP) and meropenem, an antibiotic, shows promising results in treating infections caused by carbapenem-resistant Acinetobacter baumannii. The researchers evaluated the antibacterial and antibiofilm activity of Bio-AgNP and meropenem against multidrug-resistant strains of A. baumannii. The combination of Bio-AgNP and meropenem demonstrated a synergistic and additive effect, reducing the minimum inhibitory concentration (MIC) of meropenem and inhibiting biofilm formation. This research suggests that the combination therapy could be a potential therapeutic option for treating infections caused by carbapenem-resistant A. baumannii. [Extracted from the article]
Databáze: Complementary Index