Abstrakt: |
A new study conducted by researchers at Tehran University of Medical Sciences explores the detection of Human Papillomavirus (HPV) in HPV-associated oral epithelial dysplasia (HAOED). The study examined 54 oral epithelial dysplasia specimens and found that the expression of p16 protein was not associated with the severity of dysplasia. Additionally, the study used different diagnostic methods, including immunohistochemical (IHC) study, Chromatin In Situ Hybridization (CISH) test, and Chromatin Immunoprecipitation-Polymerase Chain Reaction (ChIP-PCR) to detect HPV. The study suggests a step-by-step combination approach for diagnosing HAOED. [Extracted from the article] |