Předmět: |
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Zdroj: |
Health & Medicine Week; 4/19/2024, p3947-3947, 1p |
Abstrakt: |
New research from the University of Manchester explores the use of chromophores in photoreceptor proteins to sense light and trigger biological responses. The study focuses on the discovery that adenosylcobalamin (coenzyme B12) can act as a light-sensing chromophore, leading to the identification and characterization of a sub-family of photoreceptors called photocobilins. These photocobilins use B12 and biliverdin to sense light across the visible spectrum, and their light-triggered conversion affects enzyme activity. The findings have implications for the design of optogenetic tools and bio-photocatalysts. [Extracted from the article] |
Databáze: |
Complementary Index |
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