Autor: |
Jatoth, Ramanna, Gugulothu, Kishan, Valappil, Rasika Meloth, Nelson, Nithya, Kumar, K. Shiva |
Předmět: |
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Zdroj: |
Synlett; Apr2024, Vol. 35 Issue 7, p811-815, 5p |
Abstrakt: |
This article presents a study on the synthesis of pyrido[1,2-a:4,3-b']diindoles through a ruthenium-catalyzed coupling/cyclization reaction. The researchers investigated the reaction conditions and found that electron-donating groups and certain substitutions on the indole ring were well tolerated, resulting in good yields of the desired products. The proposed reaction pathway involves the formation of a ruthenacycle intermediate, followed by the insertion of a sulfur ylide and subsequent cyclization. The authors suggest that these pyrido[1,2-a:4,3-b']diindole derivatives may have potential pharmaceutical applications. [Extracted from the article] |
Databáze: |
Complementary Index |
Externí odkaz: |
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