| Abstrakt: |
The article discusses the properties and applications of bromamine-T (BAT), a versatile bromo-organic reagent. BAT is commonly used as an oxidimetric titrant in aqueous solutions and exhibits oxidative properties similar to hypobromites. It can oxidize a wide range of compounds such as alcohols, aldehydes, primary amines, thiols, and esters. Additionally, BAT has shown biological significance, including anticancer and microbicidal activity. It has also been used in various organic transformations such as aminobromination, amination, and aminohydroxylation. The text discusses the use of bromamine-T as a nitrene source in various reactions, including aziridination, bromination, and oxidation. Different catalysts and reaction conditions are explored, and the yields and selectivity of the reactions are evaluated. The text also includes kinetic and mechanistic studies on the oxidation reactions. Overall, bromamine-T is found to be an efficient reagent for these reactions, with varying degrees of success depending on the specific conditions and substrates used. [Extracted from the article] |
