| Abstrakt: |
Purpose: The purpose of this study was to evaluate the effectiveness of Pisonia alba Span commonly known as lettuce tree or bird catcher tree leaf extracts in controlling Aedes aegypti and Culex quinquefasciatus mosquitoes, which transmit several severe illnesses, such as dengue, Zika, chikungunya, yellow fever, West Nile virus, lymphatic filariasis and Japanese encephalitis. Methods: Sequential extraction of P. alba leaves was done using n-hexane, chloroform, and methanol. The larvicidal, pupicidal, and ovicidal activities of the extracts were evaluated against both mosquito species using standard bioassays. The concentrations of the extracts required to kill 50% of the mosquito larvae, pupae, and ova (LC50) were determined. Results: The results showed that the methanol extract of P. alba had significant potential in killing the larvae, pupae, and ova of both mosquito species, with LC50 values of 65.0 and 54.5 ppm for larvicidal activity, 73.7 and 69.7 ppm for pupicidal activity, and 78.4 and 80.0 ppm for ovicidal activity against Ae. aegypti and Cx. quinquefasciatus, respectively. The n-hexane extract demonstrated moderate larvicidal activity, while the n-hexane and chloroform extracts lacked ovicidal activity. Conclusion: The methanol extract from Pisonia alba could be a natural and eco-friendly alternative for controlling mosquito populations responsible for transmitting vector-borne diseases. Further research is warranted to determine their practical applications in controlling mosquito populations in the field. [ABSTRACT FROM AUTHOR] |
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