| Autor: |
Shinde, Jivan, Suresh, Sundaram, Kavala, Veerababurao, Ching-Fa Yao |
| Předmět: |
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| Zdroj: |
Chemical Communications; 4/11/2024, Vol. 60 Issue 28, p3790-3793, 4p |
| Abstrakt: |
A Pd-catalyzed regioselective hydroarylation of terminal alkynes containing a heteroatom has been developed via carbopalladation for the synthesis of allylic ethers, amines, and homoallylic alcohols. Moreover, hydroalkenylation of alkynes produces a variety of stereodefined 1,4-dienes with high regioselectivity. The important features of the present protocol are that it is highly regioselective, operationally rapid, and scalable with a huge substrate scope using only 3 mol% of PdCl2(PPh3)2 catalyst in the presence of a mild base KOAc. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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