| Autor: |
Udby, Peter M., Modic, Michael, Elmose, Signe, Carreon, Leah Y., Andersen, Mikkel Ø., Karppinen, Jaro, Samartzis, Dino |
| Předmět: |
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| Zdroj: |
Global Spine Journal; Apr2024, Vol. 14 Issue 3, p796-803, 8p |
| Abstrakt: |
Study design: Cross-sectional retrospective observational study. Objective: To evaluate the reliability and clinical utility of the Modic changes (MC) grading score. Method: Patients from the Danish national spine registry, DaneSpine, scheduled for lumbar discectomy were identified. MRI of patients with MC were graded based on vertical height involvement: Grade A (<25%), Grade B (25%-50%), and Grade C (>50%). All MRIs were reviewed by 2 physicians to evaluate the reliability of the MC grade. Results: Of 213 patients included, 142 patients had MC, 71 with MC-1 and 71 with MC-2; 34% were Grade A, 45% were Grade B, and 21% were Grade C. MC grade demonstrated substantial intra-rater (κ =.68) and inter-rater (κ =.61) reliability. A significantly higher proportion (n = 40, 57%) of patients with MC-1 had a severe MC grade compared to patients with MC-2 (n = 30, 43%, P <.001). Severe MC grade was associated with the presence of severe lumbar disc degeneration (DD) (Pfirrmann grade = V, P =.024), worse preoperative ODI (52.49 vs 44.17, P =.021) and EQ-5D scores (.26 vs.46, P =.053). MC alone including type was not associated with a significant difference in patient-reported outcomes (P >.05). Conclusion: The MC grade score was demonstrated to have substantial intra- and inter-observer reliability. Severe MC grade was associated with both severe DD and MC type, being more prevalent in patients with MC-1. The MC grade was also significantly associated with worse disability and reduced health-related quality of life. Results from the study suggest that MC grade is more clinically important than MC type. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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