| Autor: |
Taban Akça, Kevser, Gürbüz, Perihan, Doğan, Şengül Dilem, Emerce, Esra, Gören, Ahmet C., Polat, Rıdvan, Süntar, İpek |
| Předmět: |
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| Zdroj: |
Natural Product Research; May2024, Vol. 38 Issue 9, p1494-1502, 9p |
| Abstrakt: |
Two new sesquiterpene glucosides, 1α,6β,9β-trihydroxy-eudesm-4(15)-en-1,6-O-β-diglucopyranoside (1) and 1α,6β,9β-trihydroxy-eudesm-3-en-1,6-O-β-diglucopyranoside (2) were obtained along with the 1α,6β,9β-trihydroxy-5,10-bis-epi-eudesm-3-en-6-O-β-D-glucopyranoside (3), chlorogenic acid (4), luteolin 7-O-rutinoside (5) and luteolin 7-O- glucoside (6) from the whole plant parts of Lecokia cretica. Their structures were determined on the basis of 1 D, 2 D NMR and HRMS analyses. The in vitro cytotoxic activity of compounds 1-3 against human lung cancer cells (A549) and normal human lung cells (BEAS-2B) was determined using the MTT colorimetric assay. All the tested eudesmane derivatives were found to be inactive. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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