Researchers at University of Kentucky Have Published New Data on Abdominal Aortic Aneurysm (A highly selective mPGES-1 inhibitor to block abdominal aortic aneurysm progression in the angiotensin mouse model).

Předmět:	ABDOMINAL aortic aneurysms ANGIOTENSINS RESEARCH personnel LABORATORY mice ANIMAL disease models OLIGOPEPTIDES NEUROPEPTIDES STAB wounds AORTIC rupture
Zdroj:	Drug Week; 4/12/2024, p846-846, 1p
Abstrakt:	A recent report from the University of Kentucky discusses the potential use of a highly selective mPGES-1 inhibitor, called UK4b, in blocking the progression of abdominal aortic aneurysm (AAA) in a mouse model. AAA is a dangerous condition characterized by the permanent ballooning of the aortic artery. The study demonstrates that UK4b can effectively halt the growth of AAA in the mouse model, suggesting its potential as a treatment option. The researchers emphasize the need for anti-inflammatory drug targets and translatability in AAA research. This information may be useful for individuals researching cardiovascular diseases and conditions. [Extracted from the article]
Databáze:	Complementary Index
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