Nanchang University Researchers Add New Findings in the Area of Osteoarthritis (Glaucocalyxin A delays the progression of OA by inhibiting NF-kB and MAPK signaling pathways).

Předmět:	RESEARCH personnel CELLULAR signal transduction NF-kappa B MITOGEN-activated protein kinases OSTEOARTHRITIS
Zdroj:	Drug Week; 4/12/2024, p1312-1312, 1p
Abstrakt:	A recent study conducted by researchers at Nanchang University explored the potential of Glaucocalyxin A (GLA) as a therapeutic agent for osteoarthritis (OA). OA is a degenerative joint condition characterized by inflammation and cartilage breakdown. The study found that GLA may reduce the expression of inflammatory mediators and protect the extracellular matrix (ECM) by inhibiting the NF-kB and MAPK signaling pathways. In both in vitro and in vivo experiments, GLA demonstrated a protective effect on cartilage, suggesting its potential as a treatment for OA. Further research is needed to fully understand the therapeutic benefits of GLA for OA. [Extracted from the article]
Databáze:	Complementary Index
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