| Abstrakt: |
A recent report from researchers at the Federal University of Fronteira Sul in Chapeco, Brazil, explores the biological connections between dementia and depression, specifically focusing on the role of the amyloid beta (A beta) protein. The study highlights how small extracellular senile plaques composed of A beta protein can bind to neuronal receptors, leading to neuroinflammation and subsequent neuronal death, which is associated with dementia. The researchers also discuss the prevalence of depression in individuals with neurodegenerative diseases and the role of the hypothalamic pituitary adrenal (HPA) axis in the pathophysiological mechanisms of dementia and depression. This research provides valuable insights into the complex relationship between dementia and depression. [Extracted from the article] |
