| Abstrakt: |
A new study published in Cell reveals that the movement disorder amyotrophic lateral sclerosis (ALS) and the cognitive disorder frontotemporal lobar degeneration (FTLD) have significant molecular overlaps at the cellular level. The study, led by scientists at MIT and the Mayo Clinic, analyzed RNA expression patterns in brain samples from donors diagnosed with ALS, FTLD, or who were neurologically unaffected. The findings suggest that therapies developed for ALS may also be applicable to FTLD and vice versa. The study also identified similarities in gene expression changes between inherited and sporadic forms of the diseases, indicating common underlying molecular processes. [Extracted from the article] |
