New Findings Reported from Vanderbilt University Describe Advances in Esophagitis (Characterization of lamina propria remodeling in pediatric eosinophilic esophagitis using second harmonic generation microscopy).

Předmět:	SECOND harmonic generation EOSINOPHILIC esophagitis MEDICAL communication DIGESTIVE system diseases EXTRACELLULAR matrix proteins MICROSCOPY
Zdroj:	Gastroenterology Week; 4/9/2024, p428-428, 1p
Abstrakt:	A recent study conducted at Vanderbilt University has used second harmonic generation (SHG) microscopy to examine the structural remodeling of the extracellular matrix (ECM) in pediatric eosinophilic esophagitis (EoE). EoE is a chronic inflammatory condition characterized by an infiltration of eosinophils into the esophageal epithelium. The researchers found that alterations to the collagen fiber matrix in the lamina propria can lead to fibrosis, which is associated with complications of EoE. SHG microscopy was able to objectively quantify these alterations and provide insights into the remodeling process. The study suggests that SHG microscopy could be a valuable tool for monitoring disease progression in children with EoE. [Extracted from the article]
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu