Abstrakt: |
Researchers have submitted a patent application for a new technology called Image-seq, which enables spatially-resolved single-cell RNA sequencing. This technology overcomes limitations of existing methods by allowing image-guided cell isolation and tissue ablation. By using optical microscopy to identify regions of interest, a micropipette can be inserted to aspirate cells or ablate tissue under image guidance. Image-seq captures viable cells, leading to higher mRNA detection efficiencies and broader transcript coverage. This technology has potential applications in genetics, bone research, and health and medicine. [Extracted from the article] |