New Findings from University of Texas Medical Branch in the Area of Lung Cancer Described (DNA variants detected in primary and metastatic lung adenocarcinoma: a case report and review of the literature).

Předmět:	LITERATURE reviews LUNG cancer MUCINOUS adenocarcinoma LUNGS NON-small-cell lung carcinoma METASTASIS
Zdroj:	Cancer Weekly; 4/11/2024, p791-791, 1p
Abstrakt:	A recent study conducted by researchers at the University of Texas Medical Branch has identified genetic abnormalities in lung cancer that may serve as biomarkers for classification and prognosis. The study examined specimens from a 55-year-old white female patient with non-small cell lung cancer (NSCLC) using next-generation sequencing and chromosomal microarray assay. The researchers found a mutation in the KRAS proto-oncogene in both primary and metastatic tumor specimens, as well as several DNA copy number aberrations. These findings contribute to our understanding of the genetic drivers of NSCLC and may have implications for targeted therapies and patient outcomes. [Extracted from the article]
Databáze:	Complementary Index
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