| Abstrakt: |
Fungi cause diseases in a variety of marine animal hosts. The need for new antifungal agents arises from the rising prevalence of invasive fungal infections (IFI) and the ineffectiveness, severe side effects, and high mortality of the current antifungal agents. The present study aims to assess Caulerpa scalpelliformis seaweed extract's antifungal efficacy against human fungal infections. Using methanol solvents, the antifungal activity of marine macroalgae C.scalpelliformis was assessed against Candida albicans, Aspergillus fumigatus, Aspergillus niger, Aspergillus flavus, and Cryptococcus neoformans. C. scalpelliformis showed strong fungal activity against A. fumigatus, A. niger, and A. flavus compared to C. albicans and C. neoformans, similar to the positive control drug Amphotericin B in the current study.This is the first report from Tuticorin's Periyathalai coast. These results point to the use of green seaweed, C. scalpelliformis methanol extract as a natural antibiotic in conjunction with synthetic antibiotics, which has paved the way for the development of new anti-aspergillus, anti-cryptococcal, and anti-candidal compounds. [ABSTRACT FROM AUTHOR] |
