353 Eph/Ephrin Signaling Influences Innervation of Outer Hair Cells in Cochlea.

Autor: George, Deborah Jane, Cui, Aileen, Thiru, Shankar, Deans, Michael, Coate, Thomas M.
Zdroj: Journal of Clinical & Translational Science; 2024 Suppl 1, Vol. 8, p107-107, 1p
Abstrakt: The document titled "353 Eph/Ephrin Signaling Influences Innervation of Outer Hair Cells in Cochlea" discusses a study conducted at Georgetown University and the University of Utah that aims to understand the role of Eph/Ephrin signaling in the innervation of outer hair cells in the cochlea. The study used mice with specific genetic mutations and conducted immunostaining and imaging techniques to analyze the behavior of spiral ganglia neurons and outer hair cells. The results suggest that Eph/Ephrin signaling plays a role in guiding the neurons and influencing the growth of outer hair cells. This research could potentially lead to new therapies for hearing loss. [Extracted from the article]
Databáze: Complementary Index