| Autor: |
Coder, Scott J., Patil, Raj, McNutt, Robert A., Speroff, Theodore, Banaad-Omiotek, Geraldine, Ganger, Daniel R., Rosenblate, Howard, Kaur, Suman, Cotler, Sheldon, Jensen, Donald M. |
| Předmět: |
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| Zdroj: |
American Journal of Gastroenterology (Springer Nature); Sep2001, Vol. 96 Issue 9, p2730-2736, 7p, 3 Charts |
| Abstrakt: |
OBJECTIVES: Hepatitis C is the leading cause of chronic hepatitis in the United States. Little information is available regarding how persons with hepatitis C view health with their disease. We studied patients' perceptions about the value of hepatitis C health states and evaluated whether physicians understand their patients' perspectives about this disease. METHODS: A total of 50 consecutive persons with hepatitis C were surveyed when they presented as new patients to a hepatology practice. Subjects provided utility assessments (preference values) for five hepatitis C health states and for treatment side effects. They also stated their threshold for accepting antiviral therapy. Five hepatologists used the same scales to estimate their patients' responses. RESULTS: On average, patients believed that hepatitis C without symptoms was associated with an 11% reduction in preference value from that of life without infection, and the most serious condition (severe symptoms, cirrhosis) was believed to carry a 73% decrement. Patients judged the side effects of antiviral therapy quite unfavorably, and their median stated threshold for accepting treatment was a cure rate of 80%. Physicians' estimates were not significantly associated with patients' preference values for hepatitis C health states, treatment side effects, or with patients' thresholds for accepting treatment. In multivariate analysis, patients' stated thresholds for taking treatment were significantly associated with their decisions regarding therapy (β = -2.72 ± 1.21 p = 0.025). CONCLUSIONS: There was little agreement between patients' preference values about hepatitis C and their physicians' estimates of those values. Utility analysis could facilitate shared decision making about hepatitis C. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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