| Autor: |
Freire, Samanta, Findlay, Jacqueline, Gruner, Eva, Bruderer, Vera, Nordmann, Patrice, Poirel, Laurent |
| Předmět: |
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| Zdroj: |
Journal of Antimicrobial Chemotherapy (JAC); Apr2024, Vol. 79 Issue 4, p930-932, 3p |
| Abstrakt: |
This article discusses the emergence of multidrug-resistant Gram-negative bacteria, specifically focusing on Escherichia coli (E. coli) strains that are resistant to broad-spectrum cephalosporins. The study examines a particular E. coli strain isolated from a patient in Switzerland and investigates the mechanisms behind its resistance. The researchers found that the resistance was not due to common mechanisms such as β-lactamases, but rather a modification in the penicillin-binding-protein 3 (PBP-3) sequence. The study highlights the importance of monitoring and understanding these resistance mechanisms, especially in high-risk multidrug-resistant clones like the one identified in this study. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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