| Autor: |
Hou, Wei, Zhang, Yiyuan, Huang, Fuchao, Chen, Wanting, Gu, Yuang, Wang, Yan, Pang, Jiacheng, Dong, Hewei, Pan, Kangyin, Zhang, Shuning, Ma, Peixiang, Xu, Hongtao |
| Předmět: |
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| Zdroj: |
Angewandte Chemie; 4/8/2024, Vol. 136 Issue 15, p1-1, 1p |
| Abstrakt: |
The article titled "Rücktitelbild: Bioinspired Selenium-Nitrogen Exchange (SeNEx) Click Chemistry Suitable for Nanomole-Scale Medicinal Chemistry and Bioconjugation (Angew. Chem. 15/2024)" discusses the concept of selenium-nitrogen exchange (SeNEx) chemistry proposed by Wei Hou, Hongtao Xu, and their colleagues. The authors highlight the efficiency and versatility of SeNEx chemistry in exploring the organo-Se chemical world. The reaction between benzoselenazolones and terminal alkynes is found to exhibit modularity, robustness, mild reaction conditions, and fast kinetics. This chemistry has potential applications in nanomole-scale parallel synthesis, DNA-encoded library synthesis, and peptide and protein bioconjugation. [Extracted from the article] |
| Databáze: |
Complementary Index |
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