| Abstrakt: |
A recent study conducted in Madrid, Spain, examined the association between altered DNA methylation patterns and childhood trauma with bipolar disorder (BD) and suicidal behavior (SB) in euthymic patients. The study found that patients with BD had hypermethylation at certain sites in the discoidin domain receptor 1 (DDR1) promoter, while hypomethylation was observed at other sites. Childhood trauma was found to be a risk factor for SB, but DDR1 methylation did not mediate this association. The researchers suggest that altered DDR1 methylation may serve as a potential blood biomarker for the diagnosis and stratification of psychiatric patients. [Extracted from the article] |
