Gross and histological studies on the thymus of the grasscutter (Thryonomys swinderianus).

Autor: Korzerzer, R. M., Omar, H. A., Hena, S. A.
Předmět:
Zdroj: Savannah Veterinary Journal; 2023, Vol. 6 Issue 1, p1-8, 8p
Abstrakt: Introduction: The African grasscutter (Thryonomys swinderianus) is a nocturnal rodent of the family thryonomidae and suborder hystricomorpha. It has gained attention in West Africa as an alternative source of meat and income. Method: Twelve apparently healthy grasscutters between the ages of three and seven months old were divided into three groups according to their ages. Euthanization was achieved via chloroform inhalation. An incision was made at the neck region and the thymuses were located and identified by their prominent bilateral nature. Extracted thymuses from each animal were immediately weighed, grossly described and fixed in Bouin's fluid for 48 hours. The tissues were then prepared using standard methods. Haematoxylin and Eosin was used for routine histology while Rhodamine B aniline methylene blue was used for studying the architecture of the elastic and reticular fibres of the thymus. Results: Grossly, the thymi of the grasscutters were brightly red in colour and elongated in shape, found at the cervical region bounded externally by the maxilla. The organs were bilateral in nature with each lobe located on either side of the thoracic midline. The organ size decreased consistently as the animals advanced in age. Mean ± SEM values for thymic weights were 1.23 ± 0.048g, 0.53 ± 0.019g and 0.30 ± 0.042g at three, five and seven months of age respectively. Histologically, the thymus had two distinct zones, the cortex and medulla, the presence of eosinophilic structures known as the Hassal's corpuscles were scattered around the medulla. Significant: The findings obtained in this research would be used for disseminations of anatomical knowledge and for clinical application where necessary. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index