| Autor: |
Li, Zheyao, Zhang, Huiwen, Zhao, Lin, Ma, Yueyue, Wu, Qiufang, Ren, Haosong, Lin, Zhongren, Zheng, Jun, Yu, Xinhong |
| Předmět: |
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| Zdroj: |
Chemical Communications; 4/4/2024, Vol. 60 Issue 26, p3579-3582, 4p |
| Abstrakt: |
A DMP-initiated metal-free effective β,γ-asymmetric spirocyclopropanation of propanols strategy using oxidative iminium activation is described. This process has been realized by a synergistic amine-catalyzed one-pot cascade oxidation-Michael addition cyclopropanation for "one-pot" access to various spirocyclopropyl propionaldehydes/propanols from diverse 3-arylpropanols and α-brominated active methylene compounds under mild conditions and with high enantioselectivity (ee up to >99%). [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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