| Autor: |
Balasubramanian, R., Mohandas, Sreelekshmy, Thankappan, Ullas P., Shete, Anita, Patil, Dilip, Sabarinath, Kannan, Mathapati, Basavaraj, Sahay, Rima, Patil, Deepak, Yadav, Pragya D. |
| Předmět: |
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| Zdroj: |
Frontiers in Microbiology; 2024, p1-8, 8p |
| Abstrakt: |
Introduction: Since 2018, the Indian state of Kerala has reported four Nipah virus (NiV) disease outbreaks, raising concerns about NiV spillover from bats to the human population. Considering this, a cross-sectional study was undertaken in the Pteropus medius bat population around the Nipah virus-affected regions of Kozhikode, Kerala, India, during February, July, and September 2023. Methods: Throat swabs, rectal swabs, and organ samples were collected from bats to test for NiV using the real-time reverse transcriptase polymerase chain reaction (RT-PCR), while serum samples were screened for anti-Nipah IgG antibodies through ELISA. Results: An overall seroprevalence of 20.9% was observed in 272 P. medius bats tested. The throat and rectal swab samples of 321 bats were negative for NiV RNA. However, 4 of 44 P. medius bats tested positive for NiV in their liver/spleen samples. The partial N gene retrieved showed more than 99% similarity with the earlier reported NiV genome from Kerala state, India. Discussion: The findings of the study caution that there is a spillover risk in the region and necessary precautions should be taken. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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