| Autor: |
Kite, Thomas A., Ladwiniec, Andrew, Greenwood, John P., Gale, Chris P., Anantharam, Brijesh, More, Ranjit, Lee Hetherington, Simon, Khan, Sohail Q., O'Kane, Peter, Rakhit, Roby, Chase, Alexander, Barber, Shaun, Waheed, Ghazala, Berry, Colin, Flather, Marcus, McCann, Gerry P., Curzen, Nick, Banning, Adrian P., Gershlick, Anthony H. |
| Zdroj: |
Heart; Apr2024, Vol. 110 Issue 7, p500-507, 90p |
| Abstrakt: |
This document provides a summary of a multicenter, randomized clinical trial comparing very early invasive strategy (IS) with standard care IS in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS). The study aimed to determine if there was a difference in the primary composite endpoint of all-cause mortality, new myocardial infarction (MI), or hospitalization for heart failure (HHF) between the two groups. The trial was terminated early due to slow recruitment, but the results showed no significant difference in the primary endpoint between the two groups. The length of hospital stay was shorter in the very early IS group, but the study was underpowered to demonstrate a significant difference. The optimal timing of IS in patients with NSTE-ACS remains uncertain. The text also discusses the challenges in implementing early IS in practice and the potential economic savings associated with it. However, the trial was underpowered to detect a difference in outcomes, and further research is needed to inform clinical practice. This document is a reference to two medical articles: "Cardiac angiosarcomas: A review and a case report" published in Cancer in 1986, and "Heart" published in April 2024. The articles discuss cardiac angiosarcomas, a rare type of cancer that affects the heart. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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