Abstrakt: |
A recent study conducted at Laurentian University in Sudbury, Canada, has found that hydrogen sulfide (H2S) can protect rat cardiac cells from rotenone-induced ferroptosis, a form of cell death. The study showed that H2S reduced oxidative stress and mitochondrial damage, maintained GPx4 expression and intracellular iron levels, and promoted Fe-S cluster biogenesis. The researchers concluded that H2S could protect cardiac cells from ischemic damage by preserving mitochondrial functions and intracellular Fe-S cluster homeostasis. This research provides valuable insights into potential cardioprotective strategies. [Extracted from the article] |