Abstrakt: |
A recent study conducted by the Institute of Cellular and Organism Biology in Taipei, Taiwan, has found that high-sugar diets can impair the function of stem cells in the intestines and ovaries of female Drosophila flies. The study showed that excess dietary sugar increases glucose uptake by germline stem cells and triggers reactive oxygen species-induced JNK signaling, which reduces stem cell proliferation. Interestingly, tumor-like stem cells are less affected by high-sugar diets. These findings suggest that excess dietary sugar can damage stem cells before insulin resistance develops, potentially occurring in higher organisms as well. [Extracted from the article] |