Abstrakt: |
A recent study conducted by researchers at Jinan University in Guangzhou, China, has found that the gastric mechanosensitive channel Piezo1 plays a role in regulating ghrelin production and food intake. Ghrelin is a hormone produced by gastric X/A-like cells that stimulates appetite. The study showed that decreased expression of Piezo1 in X/A-like cells is associated with obesity, while activation of Piezo1 inhibits ghrelin production and leads to weight loss. These findings suggest that Piezo1 could be a potential target for anti-obesity therapy. The research has been published in the journal Nature Metabolism. [Extracted from the article] |