Abstrakt: |
A new report from New York City presents fresh data on age-related macular degeneration (AMD). The study found that subretinal drusenoid deposits (SDDs) in AMD are associated with decreased ellipsoid zone (EZ) thickness, indicating hypoxic damage. The researchers concluded that SDDs, especially when present without drusen, are linked to thinner EZs, suggesting progressive destruction of oxygen-sensitive mitochondria due to hypoxia. These findings support the hypothesis that SDDs are formed as a result of high-risk systemic vasculopathy. [Extracted from the article] |