Screening for depression in the Serbian general population sample: an alternative to the traditional patient health questionnaire-9 cut-off score.
| Autor: | Mihić, Ljiljana, Knežević, Goran, Lazarević, Ljiljana B, Marić, Nadja P |
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| Předmět: |
DIAGNOSIS of mental depression
CROSS-sectional method HEALTH status indicators RECEIVER operating characteristic curves RESEARCH funding POPULATION health RESEARCH methodology evaluation SCIENTIFIC observation STATISTICAL sampling RESEARCH evaluation QUESTIONNAIRES CLASSIFICATION of mental disorders DESCRIPTIVE statistics MULTIVARIATE analysis SURVEYS ANALYSIS of variance MEDICAL screening COMPARATIVE studies EPIDEMIOLOGICAL research SENSITIVITY & specificity (Statistics) |
| Zdroj: | Journal of Public Health; Mar2024, Vol. 46 Issue 1, pe15-e22, 8p |
| Abstrakt: | Background The Patient Health Questionnaire (PHQ-9) score ≥ 10 balances best sensitivity and specificity when detecting probable depression in patients. In the general population, different cut-offs are suggested. European studies on general populations validating the PHQ-9 against a diagnostic interview to detect depression are rare. Methods This was a cross-sectional observational epidemiological survey using multistage household probabilistic sampling to recruit a representative adult sample (N = 1203; age = 43.7 ± 13.6; 48.7% male). Mental disorders including current major depressive episode (MDE) were observer-rated (Mini International Neuropsychiatric Interview). The PHQ-9, quality of life (QoL), and loneliness were self-assessed. We performed validity and reliability tests of the PHQ-9 and receiver operating curve (ROC) analysis. Results The Serbian PHQ-9 was internally consistent and correlated in the expected directions with QoL and loneliness. At the cut-off score ≥ 8, sensitivity was.85 and specificity was.91. ROC analysis showed that the area under the curve was.95, indicating that the Serbian PHQ-9 can discriminate very well between persons with/without MDE. Conclusions When the PHQ-9 is assessed against the structured diagnostic interview in the general population to detect depression, the cut-off of ≥8 balances best sensitivity and specificity. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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