Research from University Clinical Center Has Provided New Study Findings on Hirschsprung Disease (Comparison of Immunohistochemical Expression of Calretinin, Map2, S-100 and Glut1 in Rectal Biopsies from Suspected Hirschsprung's Disease).

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Zdroj: Gastroenterology Week; 3/18/2024, p653-653, 1p
Abstrakt: A recent study conducted at the University Clinical Center in Prishtina, Kosovo, compared the immunohistochemical expression of calretinin, Map2, S-100, and Glut1 in rectal biopsy samples from patients suspected of having Hirschsprung's disease (HD). The study found that calretinin was the most accurate marker for diagnosing difficult cases of HD, with a 92% accuracy rate, as well as the highest sensitivity (80%) and specificity (92%). Map2 had the same accuracy as calretinin but lower sensitivity (46.67%). S-100 and Glut1 did not provide conclusive diagnoses. This research provides valuable insights into the diagnosis of HD. [Extracted from the article]
Databáze: Complementary Index