Tumor Lysis Syndrome Due to Pembrolizumab Use in Metastatic Nasopharyngeal Carcinoma.

Autor: Turhan, Aykut, Hannarici, Zekeriya, Büyükbayram, Mehmet Emin, Çağlar, Alperen Akansel, Eşdur, Pınar Çoban, Bilici, Mehmet, Tekin, Salim Başol
Předmět:
Zdroj: Archives of Basic & Clinical Research; Jan2024, Vol. 6 Issue 1, p73-76, 4p
Abstrakt: In this case, we report tumor lysis syndrome (TLS) in a patient with metastatic nasopharyngeal carcinoma treated with pembrolizumab. There are only a few studies reporting the development of TLS associated with pembrolizumab, but this is the first report to include a patient with nasopharyngeal carcinoma. We think that this case report may help us to improve our current understanding of TLS in solid tumors, particularly nasopharyngeal carcinoma. We also believe that there should be a multidisciplinary treatment and prophylactic approach for TLS, a potentially fatal complication associated with pembrolizumab treatment. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index