| Autor: |
Jha, Vikas, Kadam, Purvesh, Jain, Tisha, Bhargava, Agraj, Marick, Arpita, Saiya, Badal, Maiti, Sathi, Pandya, Siddhartha, Patel, Reetikesh, Jadhav, Namrata |
| Předmět: |
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| Zdroj: |
Umm Al-Qura University Journal of Applied Sciences (Springer Nature); Dec2023, Vol. 9 Issue 4, p494-507, 14p |
| Abstrakt: |
Artemisia pallens, an aromatic and medicinal plant occasionally referred to as Davana is a member of the Asteraceae family. Understanding the physiochemical and therapeutic properties of Davana essential oil (DEO) is the major aim of this study. Essential oil from plant material was extracted using the hydro-distillation method. Examination of the phytochemical components and several plant constituents from the whole oil were detected using GC–MS analysis and some components were Isobutyl propionate, 4,5-Dimethyl-Thiazole, Ligustrazin, Endo-2-Norborneol, Tetradecanoic acid, and Octadecanoic acid. The thermal stability of the oil was tested using thermoanalytical studies such as TG–DTA and DSC. Moreover, to comprehend the biological potential of the oil antimicrobial, antituberculosis, antimalarial, antioxidant, anticancer, and antibiofilm activities were investigated essential oil was tested for antimicrobial activity against 10 bacterial and 7 fungal strains. The antimalarial potential was evaluated against Plasmodium falciparum. Cytotoxicity of the DEO was determined against MCF-7, HeLa, and CHO cell lines employing MTT assay. Meanwhile, the DPPH assay was adopted to assess antioxidant potential, and the ability to suppress biofilm formation was also assessed. The study's findings reveal that Artemisia pallens is a reservoir of natural compounds and can be used against numerous ailments. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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