A Novel Method to Assay Aspirin in Pharmaceutical Formulations by Smartphone Camera-Based Image Scanning Densitometry.

Autor: Khan, Rimsha, Anwar, Jamil
Předmět:
Zdroj: Journal of the Turkish Chemical Society Section A: Chemistry; 2024, Vol. 11 Issue 1, p71-82, 12p
Abstrakt: This article presents a novel method for quantifying aspirin in pharmaceutical formulations using smartphone camera-based image scanning densitometry. The study aimed to develop a cost-effective and simple technique for determining aspirin concentration without the need for expensive equipment and with minimal sensitivity to ambient light. The method involved capturing colored spots formed by a reaction between aspirin and Fe(III) on filter paper or a 96-microwell plate using a smartphone camera. The integrated density of each spot was measured using a grayscale technique, and a calibration curve was created to relate integrated density to aspirin concentration. The developed technique demonstrated excellent precision and accuracy when compared to traditional methods. This study showcases the effectiveness of a cost-effective methodology for accurate aspirin quantification using a smartphone camera, even in the presence of ambient light. [Extracted from the article]
Databáze: Complementary Index