The impact of gestational weeks of Coronavirus disease 2019 (COVID-19) infection on perinatal outcomes.

Autor:	Yi, Jiao, Chen, Lei, Meng, Xianglian, Chen, Yi
Předmět:	MATERNAL health services REPRODUCTIVE health HOSPITAL care GESTATIONAL diabetes LOGISTIC regression analysis CHILD health services PREGNANCY outcomes RETROSPECTIVE studies MULTIVARIATE analysis DESCRIPTIVE statistics GESTATIONAL age PREECLAMPSIA COMPARATIVE studies PREGNANCY complications COVID-19
Zdroj:	Reproductive Health; 3/7/2024, Vol. 21 Issue 1, p1-8, 8p
Abstrakt:	Background: To evaluate the relationship between coronavirus disease 2019 (COVID-19) infection at different time points during pregnancy and perinatal outcomes. Methods: This retrospective study included 611 women who hospitalized for delivery between December 7 and April 30, 2023. Based on the different pregnancy weeks infected with COVID-19, the participants were divided into four groups: Group 1 (14–27+6 weeks gestation), Group 2 (28–36+6 weeks gestation), Group 3 (37–39+6 weeks gestation), and Group 4 (≥ 40 weeks gestation). Data including maternal demographic characteristics, clinical profiles, and perinatal outcomes were analyzed. Results: There were no significant differences in maternal demographic characteristics among the four groups (P > 0.05). Compared to Groups 3 and 4, a higher rate of fever was noted in Groups 1 and 2 (P < 0.05). The frequency of preeclampsia and gestational diabetes mellitus showed a decreasing trend as pregnancy progressing (P < 0.05). Preterm delivery and neonatal intensive care unit admission were more frequently observed in Groups 1 and 2 than in Groups 3 and 4 (P < 0.05). Multivariate logistic regression analysis demonstrated that the timing of gestation in which COVID-19 was infected was not associated with preterm delivery and neonatal intensive care unit admission (P > 0.05), whereas gestational age at COVID-19 infection was negatively associated with the occurrence of preeclampsia and gestational diabetes mellitus (P < 0.05). Conclusions: Gestational age at COVID-19 infection is a simple parameter that predicts adverse perinatal outcomes to aid clinicians in determining to provide early enhanced prenatal care and increased monitoring to reduce maternal complications. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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