Cu‐catalyzed dehydrogenative CO arylation for the synthesis of 6‐methyl benzofuro[3,2‐c] quinoline derivatives.

Autor: Makwana, Bhavik S., Morja, Mayur I., Chauhan, Prakashsingh M., Chikhalia, Kishor H.
Předmět:
Zdroj: Journal of Heterocyclic Chemistry; Mar2024, Vol. 61 Issue 3, p466-473, 8p
Abstrakt: A novel strategy for the synthesis of 6‐methyl benzofuro[3,2‐c] quinoline derivatives via copper‐catalyzed dehydrogenative CO arylation has been presented. Optimization studies have been carried out by varying various catalysts, bases, solvents, and other physical parameters. Keeping use of this dehydrogenative cross‐coupling CO arylation reaction, a variety of bioactive building blocks like fused benzofuro quinoline heterocycles were smoothly assembled in moderate to higher yields. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index