New Cancer Study Findings Have Been Reported from University of Kragujevac (Modeling 5-FU-Induced Chemotherapy Selection of a Drug-Resistant Cancer Stem Cell Subpopulation).

Předmět:	CANCER stem cells CANCER chemotherapy MEDICAL sciences MACHINE learning CANCER invasiveness
Zdroj:	Stem Cell Week; 3/11/2024, p747-747, 1p
Abstrakt:	A recent study conducted by researchers at the University of Kragujevac in Serbia has explored the role of cancer stem cells (CSCs) in chemotherapy resistance. CSCs are a subpopulation of cells within a tumor that have the ability to self-regenerate and initiate tumor growth. The study analyzed the expression of specific markers on the surface of CSCs in two cancer cell lines after treatment with 5-fluorouracil (5-FU), a common chemotherapy drug. The researchers used flow cytometry analysis and a machine learning model to simulate drug resistance. The results showed that the CSC population was enriched after chemotherapy treatment, indicating enhanced drug resistance mechanisms. The study suggests that artificial intelligence can be a valuable tool for predicting drug resistance. [Extracted from the article]
Databáze:	Complementary Index
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