Data on Antihyperlipidemic Agents Reported by Researchers at Jagiellonian University College of Medicine (Skeletal Muscle Type-dependent Effect of Atorvastatin On Foxo3a and Akt In Hypercholesterolemic Rats).

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Zdroj: Genomics & Genetics Weekly; 3/15/2024, p577-577, 1p
Abstrakt: A recent study conducted by researchers at Jagiellonian University College of Medicine in Krakow, Poland, examined the effects of atorvastatin, a commonly used lipid-lowering drug, on skeletal muscle in rats with diet-induced hypercholesterolemia. The study found that the impact of atorvastatin on muscle function depends on the type of muscle fibers present. In the gastrocnemius muscle, atorvastatin decreased levels of a protein called FoxO3a, while in the soleus muscle, it decreased levels of both FoxO3a and another protein called Akt. The study suggests that the effects of atorvastatin on these proteins are muscle type-dependent. [Extracted from the article]
Databáze: Complementary Index