| Autor: |
Bochkova, J. V., Liu, W., Brazhe, N. A., Zhgun, A. A., Maksimov, G. V. |
| Zdroj: |
Biophysics; Oct2023, Vol. 68 Issue 5, p719-724, 6p |
| Abstrakt: |
The spectra of surface-enhanced Raman scattering of D-amino acid oxidase from pig kidney were recorded and analyzed using silver nanoparticles; characteristic spectral parameters of changes in the conformation of the flavinadenine dinucleotide cofactor during activation of the enzyme by D-amino acids were revealed. It was found that the time during which changes in the conformation of the flavinadenine dinucleotide were recorded depended on the substrate specificity of the enzyme: in the presence of D-alanine, this took several seconds, and in the presence of D-serine, minutes. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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